The vast majority of the remainder of the population is mestizo (having mixed European and indigenous ancestry, most of them of Guarani descent).

[4] In the first phase, the Paraguayan population originated with the mass union of indigenous women - mainly those of Guaraní ethnicity - and the Spanish colonizers, who arrived in the 16th century: The Paraguayan people, originated in the crossbreeding of Guaraní and Spanish cultures, was governed for three hundred years under the dominion and colonial dependence of the Kingdom of Spain, with the Spaniards retaining all the rights and privileges that in most cases implied the exploitation of mestizos and natives.

[5] In a second phase, at the end of the War of the Triple Alliance - a dispute that took place between 1864 and 1870, having as protagonists the allies (Argentina, Brazil and Uruguay) against Paraguay - it is estimated that around 50% or more of the original Paraguayan population lost their lives.

Recently, in the 1970s, with the construction of the Itaipu hydroelectric power plant, there was another "wave" of immigration, especially from Brazil (mostly of German descent), but also from Asia (Koreans, Taiwanese, Japanese), and from the Arab world (Syrian-Lebanese) to the country.

[7] Paraguay has a history of other settlement, especially in the 20th century: Germans (the majority are Mennonites) with long-time Paraguayan dictator Alfredo Stroessner (President, 1954-1989) himself of German ancestry; Italians (around 40% of the total Paraguayan population is of full or partial Italian descent);[8] Japanese with Okinawans; Koreans; Chinese; Arabs; Poles; Southern Europeans; Jews; Brazilians; and Argentines are among those who have settled in Paraguay.