Whitmer offers 200 courses including honors and AP classes, 16 career training programs, 22 varsity sports, and more than 50 extracurricular activities.

Students regularly receive district, state, and national accolades in art, music, and career training competitions.

One of the school's biggest rivals are the Start Spartans; the two teams meet annually to play for the "Battle of Tremainsville".

Led by senior Ryne Smith, the 2007-2008 Panthers made an unexpected run to the state final four in basketball.

In 2011, after being picked to finish 6th in the Toledo City League, the Whitmer Varsity baseball team defeated the Start Spartans 10-8 in the final TCL Championship after falling behind 8-1.