The trust would purchase art for the City of Wichita by “American painters, potters, sculptors, and textile weavers.” The collection includes works by Mary Cassatt, Arthur G. Dove, Thomas Eakins, Robert Henri, Douglas Abdell,[2] Winslow Homer, Edward Hopper, Yasuo Kuniyoshi, John Marin, Paul Meltsner, Horace Pippin, Maurice Prendergast, Albert Pinkham Ryder and Charles Sheeler.

The Museum's lobby features a ceiling and chandelier made by Dale Chihuly.

In 2003, the museum finished another expansion project giving the building a total of 115,000 square feet (10,700 m2).

Tera Hedrick, an art historian and Wichita East High School graduate, was hired as curator in 2017 after serving in an interim role.

[3] In January 2020, the museum announced that it would begin renovation on its main entrance and lobby.