Wickes is a city[3] in Polk County, Arkansas, United States.

Wickes has historic places such as the 100-year-old City Hall, and the Lighthouse Drive-in.

According to the United States Census Bureau, the town has a total area of 6.0 km2 (2.3 mi2), of which 6.0 km2 (2.3 mi2) is land and 0.43% is water.

As of the 2020 United States census, there were 637 people, 302 households, and 250 families residing in the town.

The ethnic and racial composition of the population was 52.1% Hispanic or Latino, 44.3% non-Hispanic white, 0.4% African-American, 2.1% Native American and 2.4% reporting two or more races.

19.8% of all households were made up of individuals, and 8.1% had someone living alone who was 65 years of age or older.