[3] Wickliffe is part of the Paducah, KY-IL Metropolitan Statistical Area.

Today, Wickliffe Mounds is a state historic site and home to a research center and museum.

[4] In 1780 during the Revolutionary War, General George Rogers Clark established Fort Jefferson on a hill overlooking the Mississippi River one mile south of present-day Wickliffe.

The fort was intended to protect what was then the western boundary of the infant United States from raids by the British Army and Native Americans.

General Ulysses S. Grant directed a demonstration against the Confederate-held position at Columbus, Kentucky, in January 1862.

It served as a Union supply post for operations in the western theater of the war.