Numerous prehistoric and early-historical archeological finds indicate that the Biebrich area has been continuously inhabited since the Neolithic Age.

In the Middle Ages, from the beginning of the reign of Charlemagne, the places Biburc (Biebrich) and Moskebach (Mosbach) were part of the Königssondergau Wiesbaden, held by the Frankish king as his personal property.

King Louis the German and his entourage boarded vessels at Villa Biburg on a trip from Frankfurt to Aachen.

[2] In the 19th century, Biebrich became an important industrial center of the Rhine Main Area with the plants of Dyckerhoff Concrete (now owned by Buzzi Unicem), Kalle and Albert Chemistry (now Celanese), and Henkell (sparkling wine = Sekt).

In the economical crisis of the post-World War I Era, the small town, struck hard by unemployment of the majority of his working-class residents, merged with the bigger and much wealthier nearby spa city of Wiesbaden.