Wikieup is an unincorporated community and census-designated place (CDP) located on U.S. Route 93 in Mohave County, Arizona, United States.

U.S. Route 93 passes through the community, leading northwest 54 miles (87 km) to Kingman, the Mohave county seat, and southeast 74 miles (119 km) to Wickenburg.

Wikieup has a hot desert climate (Köppen: BWh).

Important agriculture, mining, milling, and smelting area in our early days.

"Chloride Jack" Owen in 1874, lies 18 miles south.