In 1978, Wiley was hired by the Santa Rosa, California "Press Democrat" as staff artist and editorial cartoonist.
In 1991, Wiley launched his popular Non Sequitur strip,[2] eventually syndicated to 700 newspapers as well as published on Go Comics and distributed via email.
As of February 14, at least 40 newspapers said they were dropping Non Sequitur, including The Boston Globe, the Chicago Tribune, and the Los Angeles Times.
[4] Andrews McMeel Syndication, the company that publishes Non Sequitur, confirmed to The Washington Post that numerous papers had dropped the strip and apologized for not catching the insult in the first place.
"[3] Books by Miller include Dead Lawyers and Other Pleasant Thoughts (1993), The Non Sequitur Survival Guide for the Nineties (1995), Non Sequitur’s Beastly Things (1999, foreword by Jules Feiffer), The Legal Lampoon (2002), Why We’ll Never Understand Each Other (2003), Lucy and Danae: Something Silly This Way Comes (2005), Homer, the Reluctant Soul (2005) and Extraordinary Adventures Of Ordinary Basil (2006).
In 2004, Wiley Miller, his wife Victoria Coviello, and their four Jack Russell terriers moved from Santa Barbara, California, to Kennebunkport, Maine.
He explained the relocation to Stephanie Bouchard of the Maine Sunday Telegram: Part of the attraction for both of us is in a creative sense.
[5]As of 2016, Wiley Miller and his family had moved yet again, and were no longer residing in Maine, but were living in Palmetto, Georgia.