[2] She studied at Rijksnormaalschool voor Teekenonderwijsers (National Normal School for Drawing Teachers).

Drupsteen worked as an illustrator for the Dutch women's movement and other social organizations.

She also provided illustrations for the magazine Maandblad der Vereeniging voor Verbetering van Vrouwenkleeding.

In 1908 she won the Willink van Collen competition administered by the Arti et Amicitiae.

[3] Suffering from physical and financial problems, Drupsteen moved from Amsterdam to Gelderland, eventually settling in Oosterbeek.