Wilkes Angel (February 26, 1817 in Exeter, Otsego County, New York – February 1889) was an American lawyer and politician from New York.
He attended the common schools, studied law with his father, was admitted to the bar, and practiced in Angelica.
He was a Republican member of the New York State Assembly (Allegany Co., 1st D.) in 1861.
In 1859, the county seat of Allegany County was transferred to Belmont, and after his tenure in the State Senate Angel moved his law practice there.
In 1876, he was appointed Receiver of the Belmont and Buffalo Railroad.