He played college football for the USC Trojans and was selected by the Miami Dolphins in the fourth round of the 2004 NFL draft.
Poole was also a member of the Kansas City Chiefs, Toronto Argonauts, Hamilton Tiger-Cats, Sacramento Mountain Lions and San Antonio Talons.
Best known for his standout performance against Michigan which included two sacks in the 2004 Rose Bowl (played on January 1) en route to a USC 28–14 victory.
On October 4, 2007, Poole was signed by the Toronto Argonauts of the Canadian Football League and assigned to their practice roster.
On May 25, 2011, Poole signed with the Sacramento Mountain Lions of the United Football League.