It has been inferred that he was the son of George Aglionby, who was tutor to William Cavendish, 3rd Earl of Devonshire from 1629, and who married Sibella Smith in 1635, dying in 1643.
[3] From 1669 to 1671 he acted as tutor for Sir Andrew Henley, 1st Baronet and then for Robert Paston, 1st Earl of Yarmouth.
[1] In 1698 Aglionby was attempting to negotiate a postal treaty with the French Farmer-General of Posts, in Calais.
[6] Aglionby's associates included James Brydges,[7] Abraham Hill,[8] and Matthew Prior.
[15] Dismissive of Nicolas Poussin, Aglionby mentions favourably if not at length four artists from northern Europe: Dürer, Holbein, Rubens, Van Dyck.