William Barlum Thompson (March 10, 1860 – February 12, 1941) was the Mayor of Detroit from 1907 to 1908 and again from 1911 to 1912.

[1] He graduated from the public schools of the city, and in 1876 from Goldsmith's Business University, located in Detroit.

[1] In 1887 he married Nellie Hymes; the couple had nine children:[1] Mary (born 1888), Kathleen (1889), Irene (1891), William Grover (1892), Francis Leo (1895), Helen M. (1897), Edna L. (1899), Edith R. (1905), and Virginia M.

Thompson went into partnership with his cousin John J. Barlum, forming the Cadillac Square Improvement Company.

[5] William Barlum Thompson died in Detroit on February 12, 1941.