William Bradshaw Egan (September 28, 1808 – October 27, 1860), sometimes Eagan, was an Irish American physician, politician, and orator.

Born in Killarney, Egan trained in the United Kingdom before immigrating to North America to teach school.

Egan became a noted orator and gave the celebratory speech at the opening of the Illinois and Michigan Canal.

In 1842, Egan was elected the president of an organization of Irish Americans that sought to liberate their homeland.

In 1856, he participated in the formation of the Republican Party by presiding over two of Anson Burlingame's speeches in favor of its establishment.