William C. Irvine (March 3, 1852 – July 27, 1924) was an American politician who served as the Treasurer of Wyoming as a Republican.

[2] During the Johnson County War he joined 23 gunmen and 4 cattle detectives from the Wyoming Stock Growers Association with Bob Tisdale, W. J. Clarke, and Hubert Teshemacher and later became involved in a shootout where he was wounded.

In April 1892 he was arrested for shooting O. H. Flagg, a cattle rustler, but was found not guilty.

During the 1910 gubernatorial election he managed Joseph M. Carey's campaign.

On July 27, 1924 he died in Santa Monica, California.