William Clay Cole (August 29, 1897 – September 23, 1965) was an American politician who served as a Republican representative from Missouri's 3rd congressional district from 1943 to 1949 and Missouri's 6th congressional district from 1953 to 1955.

[1] William Clay Cole was born on August 29, 1897, on a farm near Fillmore, Missouri.

[1] In 1916, Cole was a mounted scout on the Mexican border with the Missouri National Guard during the Pancho Villa Expedition and then served in France for 14 months during World War I.

[1] Cole served in the Missouri House of Representatives from 1942 to 1943, after winning a vacant seat in a special election.

[1] Cole returned to his law practice in St. Joseph and was a member of the federal Board of Veterans Appeals from 1955 to 1960.