William Cline Borden (May 9, 1858 – August 18, 1934) was an American surgeon who was a key planner behind the Walter Reed Army Medical Center.

[3][4][5] Borden published the papers "An Extemporized Section Flattener" (1887) and "The Origin and Development of the Fat Cell of the Frog" (1899).

In 1898 Borden, at the time a major, became commandant and operating surgeon of the U.S. Army General Hospital Washington Barracks.

[13][14] In the years immediately after 1905, Borden was "-probably the best informed medical officer on the subject of hospital construction.

In April 1907,[16] a year before Walter Reed opened, Borden was transferred to run a hospital in the Philippines.

[4][18] In May 1909[18] Borden was named dean of the School of Medicine and surgeon in chief of the hospital at George Washington University.

[4][19] Borden was also a member of the American College of Surgeons, which he helped found, and several other organisations.

[4] In 1992, the Center of Excellence in Military Medical Research and Education was renamed the Borden Institute in his honor.