Sir William Cooke (14 February 1572 – 2 March 1619) of Highnam Court in Gloucestershire, was an English landowner and politician who sat in the House of Commons at various times between 1597 and 1614.
In 1593 he went abroad, with a two-years’ licence to travel after his mother's unsuccessful attempt to arrange a marriage for him while he was a minor.
By January 1599 he was Purveyor to the Stable and had sufficient property to offer himself, with six men and horses, for service to Queen Elizabeth I.
He enhanced his estates by purchasing further land in and around Gloucester, and also owned Ribbesford Manor and other property in Worcestershire.
In the reign of King James I he was keeper of the lodge and herbage of Hartwell Park, Northamptonshire.