During the Anglo-Scottish war called the Rough Wooing, Eure and his sons Henry and Ralph made numerous raids against towns and farms in the Scottish Borders.

Ralph Eure defended Scarborough Castle against the Pilgrimage of Grace for 20 days in 1536 with a garrison comprising only his household servants.

William Eure and Thomas Wharton, deputy Warden of the West March had to complain to James V about the circulation of ballads against Henry which they said came from Scotland.

William spoke to Sir Thomas Bellenden, who described a performance at Linlithgow Palace before James, Mary of Guise and his bishops and council on the feast of the Epiphany.

Bellenden said after the play the King spoke to the churchmen in the audience asking them to reform their factions and manner of living, otherwise, he would send six of them into England to his uncle, Henry VIII.

[4] Beyond the regular duties of a border Warden, in 1541 William Eure was one of the commissioners appointed by Henry VIII to expel Scottish people from Northumberland following an Act of Parliament.

In June he wrote to James V of Scotland complaining that his border subjects had begun to pasture sheep and sow grain in England.

[5] In October they viewed the border along the river Tweed to the Ryden Burn's mouth and destroyed corn sown by Scots on English ground.

William noted the valued service of a Scottish armourer called Troilus Taylor and a mountain guide, Gilbert Cocklands, who had been employed leading raids into Scotland.

After showing an armed presence at Hexham, Willam planned to meet up with his colleagues at Newcastle upon Tyne on 17 November 1541 to finalise the survey.

William Eure sent Lord Hertford news of rumours he had heard from Scotsmen that the Matthew Stewart, 4th Earl of Lennox, Regent Arran and Mary of Guise had held a meeting at Stirling Castle and would reconcile their differences.

Ralph asked Hertford for a reinforcement of 1000 Yorkshire archers so that they could press forward from Haddington to be in sight of the landing place at Granton.

[10] While the army was camped near Seton Palace, Lord Maxwell requested to speak to Ralph Eure but Hertford would not allow it.

Ralph Eure, as Warden of the Middle March, was given three "pledges" or hostages for the fulfilment of the oath by 24 members of the Oliver family and their kinsmen.

[12] In October 1544, Ralph Eure gained the allegiance of Andrew Kerr of Ferniehurst and 40 followers of various names and the town of Jedburgh.

On their way back to England, they burnt the Tower of Cailing Craig, Cessford Castle, Morebattle church, Otterburn, Cowboge and other places.

Ralph Eure with Richard Bowes, Captain of Norham, and 500 men rode forward and captured or killed a number of Scots.

Subsequently, William Eure wrote to the Earl of Shrewsbury that he had escorted the Italian military surveyor Archan (Archangelo Arcano) to Coldingham.

[17] Henry Eure, in July 1544, joined George Bowes and raided Edrom, Preston, Patrick Hume's Tower and Duns.

A raid to Melrose or Jedburgh led to Ralph Eure's death at the battle of Ancrum Moor in February 1545, his companions Basford and a Scotsman John Rutherford of Edgerston cut down beside him.

[19] To avenge Ralph, Henry Eure and George Bowes went to Bowmont in Teviotdale and demolished two towers and burnt farmsteads belonging to the Laird of Molle (Mow).

Eure and Sir Cuthbert Ratcliff, Captain of the castle of Berwick; were "men of honesty and meet to serve elsewhere", but of no experience or knowledge for keeping a fortress.