William Ferguson Colcock (November 5, 1804 – June 13, 1889) was a U.S. Representative from South Carolina.

He was admitted to the bar in 1825 and commenced practice in Coosawhatchie, South Carolina.

He died in McPhersonville, Hampton County, South Carolina, on June 13, 1889.

He was interred in Stoney Creek Cemetery, South Carolina.

1860 census shows he owned 181 slaves in St. Luke’s Parish.