William Hamilton O'Dell (October 11, 1938 – January 7, 2016) was an American businessman who served as a Republican in the South Carolina Senate from 1989 until his death.
He and his wife Aedra Gayle Tisdale are the parents of two children, William B. O'Dell and Patricia Michelle Foster.
Prior to being elected to the South Carolina State Senate, O'Dell served as vice-chairman of the Ware Shoals School District 51 board, and later as director of the South Carolina Chamber of Commerce.
He also served on the Banking and Insurance, Finance, Interstate Cooperation and Labor, Commerce and Industry committees.
O'Dell died in his sleep of a heart attack on January 7, 2016.