William Hull Wickham (July 30, 1832 – January 13, 1893) was the 81st Mayor of New York City and an anti-Ring Democrat who helped to topple corrupt politician Boss Tweed.

Wickham served as Chairman of the Apollo Hall Democracy, a political group that worked to bring Boss Tweed to justice.

He also served on the Executive Committee of Seventy, a group formed by the public to reestablish honest government.

[2] He easily defeated Oswald Ottendorfer, the Independent Democratic candidate, and Salem Howe Wales, the Republican.

During his two-year tenure starting in 1875, Wickham appointed William C. Whitney to be the City of New York's legal counsel to combat political fraud.