William Henry Chaffers (August 2, 1827 – July 1894) was a Quebec businessman and politician.

He was a Liberal member of the Senate of Canada for Rougemont division from 1867 to 1894.

He was born Guillaume-Henri-Jacques Chaffers at Quebec City in 1827 and studied at the college at Chambly and the Petit Séminaire de Montréal.

He was elected to the Legislative Assembly of the Province of Canada for Rouville in an 1856 by-election.

Chaffers was elected to the Legislative Council of the Province of Canada in 1864 and named to the Senate after Confederation.