William Seward Webb (January 31, 1851 – October 29, 1926)[1] was a businessman, and inspector general of the Vermont militia with the rank of colonel.

For several years Webb practiced medicine; then forsook the profession for finance at the behest of his wife's family, establishing the Wall Street firm of W. S. Webb & Co.[1] In 1883, Webster Wagner, the president of the Wagner Palace Car Company, was crushed between two of his own railroad cars.

William Seward invited his brother H. Walter Webb to join him, which started them both on careers in the railroad business.

[1] Webb served as inspector general of rifle practice for the Vermont militia with the rank of colonel.

[1] In 1902, he intended to campaign for the Republican nomination for Governor of Vermont, but left the race in favor of Percival Clement.