The bursars' accounts of Caius College show that he was a resident at Gonville Hall, probably as a fellow, from 1548 to 1555.
In 1561 he became regius professor of civil law, and in June of that year was admitted fellow of Trinity Hall.
Soone is said to have resided at Paris, Dol, Freiburg, and Padua, and to have been a professor of law for some time at Leuven.
In Cologne, he published ‘Gulielmi Sooni Vantesdeni Auditor sive Pomponius Mela disputator de Situ Orbis’.
Part of this rare book, the ‘Novi incolæ orbis terrarum,’ is copied from Arnold Mylius and published by Ortelius in the 1570 edition of the ‘Theatrum.’ Accordingly Ortelius complained, and Soone offered explanations dated from Cologne, 31 August 1572.