Lieutenant-General William Anne Villettes, (20 August 1754 – 13 July 1808) was a senior officer of the British Army during the early nineteenth century.

He was educated in Bath, Somerset and then at the University of St Andrews, but subsequently persuaded his father to purchase a commission in the 10th Light Dragoons in 1775.

At the conclusion of the siege he was appointed governor of the town and in 1796 led a force to put down a rebellion inland, although terms were reached before he could press the attack.

In 1801 he joined the garrison of the Malta Protectorate, which had been captured the year before and in 1802 became the commander in chief of the British Army in the Mediterranean.

During this service he raised the Royal Regiment of Malta; managed the aftermath of a major ammunition explosion and in 1807 helped to put down the Froberg mutiny.