William Willoughby, 11th Baron Willoughby de Eresby

He was the son of Sir Christopher Willoughby (died c. 1498) and Margaret or Marjery Jenney (daughter of Sir William Jenney of Knodishall, Suffolk, Justice of the King's Bench).

Secondly, on 5 June 1516, he married María de Salinas, the Spanish-born lady-in-waiting to Catherine of Aragon.

[2] Grimsthorpe Castle was granted by Henry VIII to the de Eresby family on the occasion of Maria's marriage.

By his second wife, Willoughby had a daughter, Catherine, who succeeded him in the barony on his death in 1526.

When Princess Mary died in 1533, fourteen-year-old Catherine was hastily married to the Duke of Suffolk, her fiancé's father, who was thirty-five years her senior.