He joined the English mission in 1606, when he became chaplain to the Gages at Hengrave Hall, Suffolk.
He was soon arrested and imprisoned in the Tower of London (July 1607), and later in the White Lion Prison.
Supported by his brother Thomas, an ex-Jesuit, Wright disputed publicly against the oath, and the Gages, whom he had instructed, refused to take it.
When the bubonic plague ravaged London and his prison, he nursed the sick; buried the dead, and in the confusion escaped to Leicestershire, where he organized a series of missions, originally called the Residence of St. Anne.
From 1612 onwards he took to writing, and a dozen volumes are ascribed to him: three of controversy, the rest translations of the works of Martin Becan, Lessius and others.