For the Mexico City and São Paulo Grands Prix, Williams introduced a special Mercado Libre livery to commemorate its newfound partnership with the Argentine online marketplace.

[5] At the season opener at the Bahrain International Circuit, Albon and Sargeant qualified 13th and 18th respectively, finishing in 15th and 20th.

Sargeant damaged the repaired chassis in the following Japanese Grand Prix during the first free practice session.

[8] Sargeant was dropped from the Italian Grand Prix onwards with Williams Academy driver Franco Colapinto stepping up from his Formula 2 campaign to take his place for the remainder of the season.

[9] At Azerbaijan Grand Prix, the team achieved their first double-points finish of the season with Albon in seventh and Colapinto in eighth.