[7] When she was fifteen, she temporarily lost the sight in her left eye, and permanently in her right;[8] she had contracted acanthamoeba, which ate three out of four layers of her cornea.
[7] At the time, she was interested in a career in graphics, but changed course after listening to her favourite songs while blind and hearing things she had not heard before.
[3] In 2019, she and Kenya Grace made the Top 21 in ISawItFirst,[9] a nationwide search in collaboration with Capital Xtra intended to find new women musicians, winning a music video for "Ctrl Alt Dlt".
After being used in a TikTok advert, the song received over 1,000 abusive comments,[8] which Kayne responded to by writing her second single, "I Don't Wanna Know",[12] which she released on 22 July 2021.
[13] In September,[3] she won an Ivor Novello Rising Star Award in 2021, along with mentorship from Nile Rodgers,[14] and later that month "Two Seater" turned up on the FIFA 22 soundtrack.