Willow Street is an unincorporated community and census-designated place (CDP) in Lancaster County, Pennsylvania, United States.

As time passed and the town grew, the road was widened and sidewalks were installed, which required the trees be removed.

One tall willow tree was situated behind Kendig Square Plaza, but it was downed during a wind storm during late February/early March 2018.

It is the location of the Hans Herr House, the oldest homestead in Lancaster County, and also the Martin Meylin Gunshop, where the long rifle was first made.

Pennsylvania Route 272 (Willow Street Pike) is the main highway through the community.

U.S. Route 222 joins PA 272 in the north part of the CDP (shown as "Mylin Corners" on USGS topographic maps) and leads north into Lancaster but southeast 10 miles (16 km) to Quarryville.