Wilson's Mills is a town in Johnston County, North Carolina, United States.

It is 6 miles (10 km) north of Smithfield, the county seat.

U.S. Route 70 passes through the southern side of the town, leading northwest 26 miles (42 km) to Raleigh and southeast 6 miles (10 km) to Interstate 95 at Selma.

[4] As of the 2020 United States census, there were 2,534 people, 840 households, and 648 families residing in the town.

19.8% of all households were made up of individuals, and 7.3% had someone living alone who was 65 years of age or older.