In 1906 the wooden-frame building was demolished, and a new Wilson High School was built on Athens Street, away from downtown in a black residential neighborhood.

The school moved to North Irby Street in 1956 and to its current location on Old Marion Highway in 1982.

[3] Wilson's We the People: The Citizen and the Constitution debate team won the annual state competition in 2001, 2003, 2004, 2005, and 2010.

Wilson has won the Pee Dee Regional Academic Challenge AAA/AAAA championship eleven out of the past twelve years,[when?]

The boys' basketball and varsity football teams won AAA state championships in 2007.