[4] The station was originally built in 1924 by the Atlantic Coast Line Railroad, designed by architect A.M. Griffin, and contained a separate REA Express building.

[5] In 2024, Amtrak completed $4 million in renovations to the station, in partnership with the Federal Railroad Administration (FRA) and in cooperation with the City of Wilson, North Carolina Department of Transportation, and CSX.

On October 24, 2024, the station was renamed at a dedication ceremony in honor of G.K. Butterfield in recognition of his decades-long public service to Wilson.

The facility is open daily at 9:00am–5:00pm, which includes the ticket office, passenger assistance, baggage service and the waiting area.

[8] Located cater-cornered from the station is the Wilson Transportation Center, providing local and intercity bus services.