Wilsonville is a town in southeastern Shelby County, Alabama, United States, located northeast of Columbiana.

Wilsonville is named after the earliest settler in the area, Elisha Wilson.

Alabama State Route 25 is the main highway through the town, running northeast to southwest through the downtown area.

As of the 2020 United States census, there were 1,857 people, 841 households, and 603 families residing in the town.

At the time of the census[9] of 2010, there were 1,867 people, 610 households, and 486 families residing in the town.