Windham (sometimes listed as Wyndham) performed six voyages for the EIC between 31 March 1801 and 25 June 1817, sailing to India from England, and back.

On 8 October 1798, the EIC accepted a tender by William Wilson of Windham of 820 tons (bm) for six voyages.

On her return leg she crossed the Second Bar on 21 January 1802, reached Saint Helena on 12 April, and The Downs on 12 June.

[10] On the way the convoy ran into severe weather with the result that the Prince of Wales, which had also left St Helena with the rest, foundered with the loss of all on board; this had been her maiden voyage.

[2] During the Mauritius campaign of 1809–1811 the French frigate Vénus captured her and two other Indiamen Charlton and United Kingdom in the action of 18 November 1809.

Windham resumed her journey, only to fall afoul of the French frigate Bellone near Johanna Island at the action of 3 July 1810.

HMS Sirius recaptured Windham at the Battle of Grand Port on 21 August 1810 and sent her with a prize crew to Île Bourbon.

Windham, Blythe, master, General Hewett, and Wanstead left England on 23 August 1813, initially under escort by HMS Akbar.

José Antonio Álvarez Condarco, agent of the Chilean government in London, arranged the purchase of the ship and the recruitment of unemployed naval officers and crew.

Although the attack on Esmeralda cost Captain O'Brien and his boarding party their lives, Lautaro did succeed in lifting the Spanish blockade of Valparaíso.

[19] Later that year Lautaro, under the American, Captain Charles Wooster, was in the squadron under Commodore Blanco Encalada that surprised the relieving Spanish fleet at Talcahuano on 28 October.

[22][23] In the first half of 1819, after Lord Cochrane had taken command of the Chilean navy, Lautaro, under Captain Martin Guise, took part in the blockade of Callao, though a planned cutting out expedition against the Spanish fleet in the harbour was not successful.

[24] On 7 November, returning to Peru, Lautaro and Galverino successfully attacked the shipping in the defended port of Pisco.

[25] In 1820 she participated in the Freedom Expedition of Perú, culminating in the successful cutting out at Callao of the Spanish flagship Esmeralda by Cochrane and Guise on 5 November.

During a period of considerable unrest on Chilean Navy vessels due to lack of pay, Lautaro was involved in the seizing by Cochrane of the Peruvian schooner Sacramento.

The liberator José de San Martín had sent Sacramento to Ancón Bay with the entire currency of the State Treasury and the mint at Lima.

Lautaro was able to sail later in 1822 to recover Valdivia although, on 23 October in Talcahuano, the crew mutinied against Captain Wooster, who had returned to Chilean service and to his former ship that year.

In addition to Lautaro, the expedition comprised the armed schooners Moctezuma and Mercedes, and the transports Ceres, Esther (of Liverpool, Davis, master), Santa Rosa, and Sesostris.