[1] Located in southeast Wisconsin, the district comprises parts of eastern Kenosha County and southeast Racine County, including most of the city of Kenosha and the south side of the city of Racine, along with the villages of Somers and Sturtevant, most of the village of Mount Pleasant, and the northern half of the village of Pleasant Prairie.

The district also contains Kenosha Regional Airport, Johnson Wax Headquarters, the Foxconn in Wisconsin industrial park, Regency Mall, Carthage College, and the University of Wisconsin–Parkside campus.

[2] Robert Wirch is the senator representing the 22nd district.

[6] A partial list of all previous senators from this district:[7] Note: the boundaries of districts have changed repeatedly over history.

Previous politicians of a specific numbered district have represented a completely different geographic area, due to redistricting.