Set in contemporary New York City, the occult police drama centers on Sara Pezzini (Yancy Butler), a brooding and willful homicide detective who is the reluctant inheritor of an ancient, symbiotic weapon that grants her superhuman powers.

[1] After one of Gallo's henchmen assaults her partner, Danny Woo (Will Yun Lee), Sara pursues him into a museum where the artifacts of Joan of Arc are among those displayed.

While searching for Gallo's man, Sara is momentarily transfixed by a metal gauntlet in a display case – and is startled by a mysterious figure (Eric Etebari) who vanishes as quickly as he appears.

[2] Executive producer Stone had taken Top Cow's project to Warner Bros. Television, which agreed to finance development and took Witchblade to TNT, a sister company in the Time-Warner family.

[8] As well as original music by Joel Goldsmith, the soundtrack includes songs by U2 ("Mysterious Ways"), Beth Orton ("She Cries Your Name"), Rob Zombie ("Living Dead Girl") and The Guess Who ("American Woman").

"Emergence", the episode that begins the second season of the Witchblade television series, uses scenes from the pilot film in presenting an alternative scenario after Sara uses the powerful weapon to reverse time.

Although the widescreen Region 1 DVD set from Warner Home Video features an all-new soundtrack selected by the executive producer, the songs in the series pilot were not replaced.