[1] As of 2021, McFarlane featured products with licenses of games and companies such as DC Comics, Demon Slayer: Kimetsu no Yaiba, Bleach, Warhammer, Mortal Kombat, Disney, The Princess Bride, and Avatar: The Last Airbender.

[4] Production began with action figures based upon Todd McFarlane's Spawn comic series and has since grown to feature a large number of licensed property lines including The Simpsons and "Movie Maniacs" (which features numerous famous horror icons such as Freddy Krueger, Jason Voorhees, Michael Myers, The Terminator, Leatherface, and The Thing), as well as other characters and lines like basketball, hockey and baseball legends, along with characters from video games such as Soulcalibur, Onimusha, and Metal Gear Solid.

[5] The company has produced original works, giving a grotesque twist to fairy tale stories such as The Wonderful Wizard of Oz, and historical figures.

Series McFarlane have merchandised include Akira, Tenchi Muyo, Tokyo Ghoul, Attack on Titan[13] and Naruto Shippuden.

[4] In 2004, the third series, subtitled 6 Faces of Madness, used historical killers and madmen as its theme, generating vividly detailed figurines of the 5th-century conqueror Attila the Hun, American "Wild West" gunslinger Billy the Kid, the "mad monk" Rasputin, the British serial killer Jack the Ripper, the Hungarian "Blood Queen" Elizabeth Bathory, and the real-life inspiration for Dracula, Vlad the Impaler.

The figures were of classic children’s stories, including Peter Pumpkin-Eater, Hansel & Gretel, Little Miss Muffet, Humpty Dumpty, & Red Riding Hood, and incorporated many of the gory elements that consumers had come to expect from McFarlane, but with a sense of ironic humor.

Like the previous series, the figures all are twisted variations of Christmas, including a hunchback and obese Santa Claus who hides a lifeless skull under a gas mask-like headpiece and wears contraptions on his hands similar to the glove of Freddy Krueger.

Series three would further push the boundaries of character selection into fantasy, with Edward Scissorhands, straight action with Shaft, and back into cult/sci-fi with Escape from L.A..[citation needed] In February 2024, it was announced that McFarlane would release more figures in their Movie Maniacs line, including characters from NBCUniversal Movies such as Andy Stitzer from The 40-Year-Old-Virgin, The Dude from The Big Lebowski, and Jake Blues from The Blues Brothers.

The number of music figures produced by the company continued to grow in number, diversity, and quality in the following years as they acquired the action figure rights to famous properties such as the Beatles, Rob Zombie, Alice Cooper, Ozzy Osbourne, Metallica, Slash, Iron Maiden's mascot Eddie, Jimi Hendrix, Freddie Mercury and Elvis Presley.

[35] In 2005, McFarlane acquired the rights held by rival manufacturer Playmates Toys to produce figures based on the popular Fox TV series The Simpsons.

[25] In 2017, McFarlane Toys agreed a deal to produce action figures and role play items based on the popular Star Trek franchise.

[36] Controversy ensued when the company's Star Trek: Discovery phaser toy was cancelled just months before its scheduled release date.

[citation needed] McFarlane Toys has produced a number of products based on video games, including Metal Gear Solid, Soulcalibur II (The Xbox version of which featured McFarlane's own Spawn as a guest character), Halo, Five Nights at Freddy's, Call of Duty, Destiny, Cuphead, Borderlands and Assassin's Creed.

[38] The toys proved very popular, and Todd McFarlane later announced that the increased articulation scheme would become standard in the company's product from then on, including their upcoming line of Mortal Kombat 11 figures.

[40] In February 2019, it was announced that McFarlane Toys had secured the rights to create 6"-12" collector figures based on the various comic books, movies, cartoons, live-action TV shows and video games featuring DC's characters.

[41] In a subsequent interview with IGN, Todd McFarlane confirmed that the new figures will target the same collectors who bought other 6" superhero toy lines, such as Mattel's DC Universe Classics or Hasbro's Marvel Legends.

The release includes Bizarro & Batzarro in a combined pack, Nightwing, Superman, and Red Robin Jokerized Gold label.

The line includes Val Kilmer's Batman, Chris O'Donnell's Robin, Jim Carrey's Riddler, and Tommy Lee Jones' Two-Face, as well as other figures.

The figures did not depict actual people so much as it did their professions, named simply by their job descriptions, such as "Army Ranger" or "Navy SEAL."

All were of stern-looking males in full military gear, with highly detailed weapons and accessories modeled after the exact materials each soldier would be carrying in real life.

[4] In 2000, McFarlane Toys produced figures based on Maurice Sendak's classic children's book Where the Wild Things Are.

[59] A number of McFarlane's figures have attracted criticism and led to boycotts for the subject matter they depict, such as Death Row Marv, which depicts the central character from the graphic novel Sin City in the electric chair, which includes a toggle switch that allows the user to "execute" the character, who shakes and speaks as if being electrocuted when the switch is flipped.