[1] It is the main teaching hospital for the Australian National University Medical School.

In 1942, the United States Army Medical Corps took over construction and commissioned it as an American military hospital.

[2] On 13 July 1997 the superseded buildings on the Acton peninsula were demolished by implosion, killing a 12-year-old girl named Katie Bender who was hit by flying debris.

[4] In 2010, the second operating theatre in Australia capable of performing intraoperative MRI scanning during surgery was completed.

[citation needed] In July 2022, construction commenced for the Surgical Procedures, Interventional Radiology and Emergency (SPIRE) Centre, with an estimated $661 million cost.

[9] Free public parking is available in numerous locations across the hospital campus including a multi-storey car park to the south of the Canberra Region Cancer Centre between Bateson Road and Hospital Road.