Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis.

For example, oroxindin is a wogonin glucuronide isolated from Oroxylum indicum.

[2] Preliminary in vitro studies have shown pharmacological effects that indicate wogonin may have anti-tumor properties.

[6] It acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with a binding affinity of Ki 0.92μM and an IC50 value of 1.26μM which is about 100x less potent than diazepam (IC50 value of 0.012μM).

[2][6] The LD50 of pure Wogonin in mice is 3.9 grams per kilogram of body weight suggesting low toxicity [7]