Wolff's law

[2][3] The internal architecture of the trabeculae undergoes adaptive changes, followed by secondary changes to the external cortical portion of the bone,[4] perhaps becoming thicker as a result.

[5] This reduction in bone density (osteopenia) is known as stress shielding and can occur as a result of a hip replacement (or other prosthesis).

[6] Mechanotransduction leading to bone remodeling involves the steps of mechanocoupling, biochemical coupling, signal transmission, and cell response.

[7] The specific effects on bone structure depend on the duration, magnitude, and rate of loading, and it has been found that only cyclic loading can induce bone formation.

[8] Osteocytes are the most abundant cells in bone and are also the most sensitive to such fluid flow caused by mechanical loading.

Tennis players often use one arm more than the other