After his father's death in 2020 led to the disbandment of Van Halen, he began to focus on his solo project Mammoth WVH, in which he performs all instruments and vocals.

He often watched his father rehearse, and at times would try to play his uncle Alex's drum kit, whereupon the latter would give him a few lessons.

He also made guest appearances during some dates of Van Halen's 2004 tour, appearing during his father's extended guitar solo spot and playing with him the instrumental "316"[citation needed] (from the album For Unlawful Carnal Knowledge), which refers to his birthday.

For a 13-year period ending in 2004, Eddie Van Halen collaborated with Peavey on a line of guitars, the Wolfgang series, named after his son.

Sevendust guitarist Clint Lowery revealed in a June 2019 tweet on Twitter that Van Halen would play on his solo debut.

The LP showcased his talents as a songwriter and musician with Van Halen writing every song and playing every instrument on the studio album.

"[17] Both "Distance" and his second single, "Don't Back Down", debuted at #1 on the Billboard's Mainstream Rock Airplay Chart.

When he began playing bass, his inspirations were Les Claypool of Primus and Justin Chancellor of Tool.

He also enjoys Chris Wolstenholme of Muse, John Entwistle of The Who, Jack Bruce of Cream "and all of the classic players".

[19] Named in homage to the classical composer Wolfgang Amadeus Mozart, he is the only child of Dutch-American guitarist Eddie Van Halen and American actress Valerie Bertinelli.

[21] Wolfgang Van Halen announced his engagement to longtime girlfriend Andraia Allsop on July 6, 2022.