Wonohaquaham, also known as Sagamore John, was a Native American leader who was a Pawtucket Confederation Sachem when English began to settle in the area.

A few years after his father's death, Wonohaquaham became sachem of Mishawum, which consisted of the land near the Mystic River, including present-day Chelsea, Charlestown, Malden, Everett, Revere, Somerville, Woburn, and Stoneham as well as parts of Medford, Cambridge, Arlington, and Reading.

[1][4] On or just before December 2, 1633, Wonohaquaham and thirty of his people died of smallpox,[2][8] part of an outbreak that had also killed Massachusett sachem Chickatawbut the previous month, and would go on to devastate the native population of Piscataqua.

[8] Prior to his death, Wonohaquaham asked Reverend John Wilson to raise his two sons (only one of which survived the outbreak) and teach them of the Christian faith.

[8] In contrast, Wonohaquaham's father Nanepashemet was known to have been killed in a siege of his palisade fort in 1617 in Medford, where his burial site was discovered in 1621 by Edward Winslow.