He was the Democratic nominee for governor of Indiana in the 2020 election, losing to incumbent Republican Eric Holcomb.

[4] Myers also supported a law that called for recording the names of those infected with HIV/AIDS and quarantining "recalcitrant carriers" of the disease.

[11] After his opponents (State Senator Eddie Melton and local business owner Josh Owens) dropped out of the race, he became the only remaining Democrat running for governor in Indiana.

[17] Myers garned approximately 32% of the vote which marked the worst performance by a Democratic candidate for governor in Indiana history.

His son, Zachary A. Myers, is a lawyer and the United States Attorney for the Southern District of Indiana.