Headquartered in Dumbo, Brooklyn, it has offices in Portland, Oregon, São Paulo, Rio de Janeiro, Copenhagen, Belgrade, Los Angeles and Atlanta, Georgia.

Notable current and past clients include Acorns, Aesop, ALDO,[2] Apple, Bottega Veneta, Claro, Disney, Grupo Globo, Google, Epic Games, Gatorade, Hippo, IKEA,[3] Mailchimp, Mercedes-Benz, MTA,[4] Nike, Planned Parenthood, T-Mobile and Virgin America.

[8][9] In 2019, the firm expanded its presence in Europe, opening an office in Copenhagen[10] around the same time IKEA named Work & Co as their digital product agency-of-record.

[24] The company has been vocal about its stance in supporting social movements related to DACA and immigration, sanctuary cities, women's health, climate change, and voting rights.

[44] After winning a Bronze Lion in Design,[45] Virgin America then named Work & Co their digital agency of record, tasking them with the redesign other products including their mobile app and in-flight entertainment system.

[47][48] The Live Subway Map is an interactive digital product that builds upon the iconic designs by Unimark International and Michael Hertz Associates.

It combines the geometric clarity of Massimo Vignelli’s diagram with the geographical and organic curves by Hertz, and connects to a live database for real-time service updates.

[65] In 2019, Work & Co partnered with Planned Parenthood for America to determine ways in which technology could extend the non-profit’s reach and impact among teen populations.

[66] Work & Co conducted research with teenagers for several months, testing a series of concepts before establishing a plan on “Roo,” a gender-neutral, AI-powered chatbot providing private and doctor-reviewed sexual health information.

[69] Fashion brand Givenchy tapped Work & Co to improve their digital capabilities, including a comprehensive rebrand and buildout of their e-commerce products.