In 1952, in response to Decree 900, land reforms attempting to end feudal working conditions for peasant farmers in Guatemala, Wrigley's discontinued purchasing chicle from that country.

Wrigley's announced the closure of its Santa Cruz, California manufacturing plant in April 1996.

The 385,000-square-foot manufacturing facility was put on the market in October 1996 for US$11.3 million, or about $30 a square foot.

[10] Financing for the transaction was provided by Berkshire Hathaway, Goldman Sachs, and JPMorgan; Berkshire Hathaway held a minority equity investment in Wrigley until October 2016, when Mars took full control over the company.

[11][12][13][14] The Wrigley Building on Michigan Avenue, a landmark on Chicago's Magnificent Mile, was the company's global headquarters until 2011, when it was sold to an investor group that included Zeller Realty Group as well as Groupon co-founders Eric Lefkofsky and Brad Keywell.

The popular premium, chewing gum, began to seem more promising, prompting another switch in product focus.

[9] On June 26, 1974, a Marsh Supermarket in Troy, Ohio installed the first bar code scanning equipment.

[18] (This pack of gum is now on display at the Smithsonian Institution's National Museum of American History.)

[9] In 2005, Kraft Foods sold the Life Savers and Altoids businesses to Wrigley in exchange for $1.5 billion as part of a reorganization plan.

The WSI investigates the effects of gum chewing on weight management, stress relief, concentration, and oral health.

[9] Dushan Petrovich (1954–) succeeded Perez almost immediately after Mars, Incorporated's 2008 purchase of Wrigley.