He caught the eye of Gu Shao, a noted judge of character, and became his friend[5] and the celebrated expert on physiognomy, Zheng Yu.
[6] In 209,[7] after Sun Quan was nominally appointed General of Chariots and Cavalry (車騎將軍) by the Han central government, he named Wu Can as his Registrar (主簿).
Wu Can was later given greater responsibilities, serving as the Prefect (令) of Shanyin County (山陰縣; present-day Shaoxing, Zhejiang) and as Colonel Who Advises the Army (參軍校尉).
[9] After the Battle of Dongkou, Wu Can was appointed as the Administrator (太守) of Kuaiji Commandery along the southern shore of Hangzhou Bay.
Throughout the remaining years of his career, Wu Can held the following offices consecutively: Colonel of a Cavalry Garrison (屯騎校尉), Minister Steward (少府) and Crown Prince's Tutor (太子太傅).
Sun Ba and Yang Zhu responded to this threat to their positions, attacked Wu Can who was subsequently arrested for his correspondence with Lu Xun , imprisoned and eventually executed.