Wu Han studied with Raymond Hanson, Rudolf Serkin, Herbert Stessin, Lillian Kallir, and Menahem Pressler and attended the Marlboro Music School and Festival for two summers.

Wu Han's repertoire has expanded to include works by composers Bruce Adolphe, Lera Auerbach, Gabriella Lena Frank, Pierre Jalbert, Augusta Read Thomas, and George Tsontakis.

[citation needed] In 2004, Wu Han and Finckel were appointed Artistic Directors of the Chamber Music Society of Lincoln Center in New York City.

[4][5] The Wolf Trap Foundation for the Performing Arts appointed Wu Han as the Artistic Advisor for Chamber Music in the Barns in 2018, and she continues to curate the series.

In 2022, she was appointed as the Artistic Director of La Musica in Sarasota, Florida and was invited to serve on the jury of the Van Cliburn International Piano Competition.