It was also during her university years that she was diagnosed with hepatitis B. Wu established the Weizhiming Women’s Center in Hangzhou in 2014 and is its executive director.

Previously, Wu was the project leader for women’s rights programs at the Beijing Yirenping Center, an organization dedicated to social justice and public health, and a staff member of the Beijing Aizhixing Institute, China’s leading NGO on the rights of people infected with HIV/AIDS.

[2] In 2015, to mark International Women's Day on 8 March, Wu and some other Chinese feminism activists, including the Five, planned to hand out pamphlets on public buses and subways to raise awareness on sexual harassment.

Hillary Clinton, running as a democratic presidential candidate at the time, tweeted "The detention of Chinese women's activists must end" and described the government action as "inexcusable.

[10] When the #MeToo movement gathered momentum globally, Wu offered support and advice to activists campaigning for policies to prevent sexual harassment in Chinese universities.